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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 94923Generated: October 27, 2026

Dichloromethane → [3,8-difluoro-4-hydroxy-7-oxo-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-4-yl]methyl 4-methylbenzenesulfonate

https://huagongshe.com/reaction/94923

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactant4-Toluenesulfonyl chlorideHCID 7397—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantDibutyltin oxideHCID 61221—
Reactant3,8-Difluoro-4-hydroxy-4-(hydroxymethyl)-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-oneHCID 23634274—
Product[3,8-difluoro-4-hydroxy-7-oxo-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-4-yl]methyl 4-methylbenzenesulfonateHCID 86614148—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-7b2f598e107643da8dd717e91e9d76f1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)