Dichloromethane → [3-(3,4-Dihydro-2H-quinolin-1-yl)-pyridin-2-ylmethyl]-(3,5-dimethyl-pyridin-2-ylmethyl)-amine

Reaction equation

[CH3:19][c:20]1[c:21]([CH:27]=[O:28])[n:22][cH:23][c:24]([CH3:26])[cH:25]1.[Cl:29][CH2:30][Cl:31].[N:1]1([c:11]2[c:12]([CH2:17][NH2:18])[n:13][cH:14][cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21>>[N:1]1([c:11]2[c:12]([CH2:17][NH:18][CH2:27][c:21]3[c:20]([CH3:19])[cH:25][c:24]([CH3:26])[cH:23][n:22]3)[n:13][cH:14][cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 187316833,5-Dimethylpyridine-2-carbaldehyde

HCID 67271944C-[3-(3,4-dihydro-2H-quinoline-1-yl)pyridine-2-yl]methylamine

Product 1

HCID 67272814[3-(3,4-Dihydro-2H-quinolin-1-yl)-pyridin-2-ylmethyl]-(3,5-dimethyl-pyridin-2-ylmethyl)-amine

Sources & evidence

ORD record: ord-e489eb468e4c4acb9ab9d4f31dbdab13
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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