3-(Pyridin-4-yl)propanoic acid → 4-hydroxy-1-(3-nitrophenyl)-3-[1-oxo-3-(pyridin-4-yl)propyl]-1,8-naphthyridin-2(1H)-one
Reaction equation
[OH:1][c:2]1[cH:3][c:4](=[O:21])[n:5](-[c:12]2[cH:13][c:14]([N+:18](=[O:19])[O-:20])[cH:15][cH:16][cH:17]2)[c:6]2[n:7][cH:8][cH:9][cH:10][c:11]12.[n:22]1[cH:23][cH:24][c:25]([CH2:28][CH2:29][C:30](=[O:31])[OH:32])[cH:26][cH:27]1>>[OH:1][c:2]1[c:3]([C:30]([CH2:29][CH2:28][c:25]2[cH:24][cH:23][n:22][cH:27][cH:26]2)=[O:31])[c:4](=[O:21])[n:5](-[c:12]2[cH:13][c:14]([N+:18](=[O:19])[O-:20])[cH:15][cH:16][cH:17]2)[c:6]2[n:7][cH:8][cH:9][cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-9d27c08f2df84131ace940ac084534d3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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