Ethanol → 2-(4-(Difluoromethoxy)phenyl)ethan-1-ol

Reaction equation

[BH4-:14].[CH3:16][CH2:17][OH:18].[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH2:10][CH:11]=[O:12])[cH:8][cH:9]1)[F:13].[Na+:15]>>[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH2:10][CH2:11][OH:12])[cH:8][cH:9]1)[F:13]

Participants

Reactant 4

HCID 702Ethanol

HCID 923Sodium Ion

HCID 28123Borohydride

HCID 592595402-(4-(Difluoromethoxy)phenyl)acetaldehyde

Product 1

HCID 552662382-(4-(Difluoromethoxy)phenyl)ethan-1-ol

Sources & evidence

ORD record: ord-cf422f9a048f409091d612cf5af23d23
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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