Benzene, 1,2-dichloro-3-fluoro- → 4-(2,3-Dichlorophenyloxy)-2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine

Reaction equation

[CH3:1][c:2]1[cH:3][c:4]2[c:5]([o:13]1)[CH2:6][N:7]([CH3:12])[CH2:8][CH2:9][CH:10]2[OH:11].[Cl:14][c:15]1[c:16]([F:22])[cH:17][cH:18][cH:19][c:20]1[Cl:21]>>[CH3:1][c:2]1[cH:3][c:4]2[c:5]([o:13]1)[CH2:6][N:7]([CH3:12])[CH2:8][CH2:9][CH:10]2[O:11][c:16]1[c:15]([Cl:14])[c:20]([Cl:21])[cH:19][cH:18][cH:17]1

Participants

Reactant 2

HCID 119011Benzene, 1,2-dichloro-3-fluoro-

HCID 684101192,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol

Product 1

HCID 250277984-(2,3-Dichlorophenyloxy)-2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine

Sources & evidence

ORD record: ord-ae67230565554c97826b644c76f46be2
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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