Morpholine → 4-(2-Chloro-6-methoxyphenyl)-9-hydroxy-6-[2-(4-morpholinyl)ethyl]pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

Reaction equation

[CH2:36]1[CH2:37][O:38][CH2:39][CH2:40][NH:41]1.[CH3:1][S:2]([O:3][CH2:6][CH2:7][n:8]1[c:9]2[cH:10][cH:11][c:12]([OH:35])[cH:13][c:14]2[c:15]2[c:16]3[c:17]([c:18](-[c:21]4[c:22]([Cl:29])[cH:23][cH:24][cH:25][c:26]4[O:27][CH3:28])[cH:19][c:20]12)[C:30](=[O:34])[NH:31][C:32]3=[O:33])(=[O:4])=[O:5]>>[CH2:6]([CH2:7][n:8]1[c:9]2[cH:10][cH:11][c:12]([OH:35])[cH:13][c:14]2[c:15]2[c:16]3[c:17]([c:18](-[c:21]4[c:22]([Cl:29])[cH:23][cH:24][cH:25][c:26]4[O:27][CH3:28])[cH:19][c:20]12)[C:30](=[O:34])[NH:31][C:32]3=[O:33])[N:41]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1

Participants

Reactant 2

HCID 8083Morpholine

HCID 867601972-(4-(2-Chloro-6-methoxyphenyl)-9-hydroxy-1,3-dioxo-2,3-dihydropyrrolo[3,4-c]carbazol-6 (1H)-yl)ethyl methanesulfonate

Product 1

HCID 219804724-(2-Chloro-6-methoxyphenyl)-9-hydroxy-6-[2-(4-morpholinyl)ethyl]pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

Sources & evidence

ORD record: ord-88427019b25d4829a9fe6cbde1af3c37
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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