Acetone → 5-fluoro-1-methyl-1H-indole-3-carboxylic acid

HRID 957129

Reaction equation

HRID 957129 reaction equation
[CH3:20][C:21](=[O:22])[CH3:23].[F:1][c:2]1[cH:3][c:4]2[c:5]([CH:12]=[O:13])[cH:6][n:7]([CH3:11])[c:8]2[cH:9][cH:10]1.[K+:19].[Mn:14](=[O:15])([O-:16])(=[O:17])=[O:18]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([C:12](=[O:13])[OH:15])[cH:6][n:7]([CH3:11])[c:8]2[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 180AcetoneHCID 813Potassium CationHCID 24401PermanganateHCID 13820095-fluoro-1-methyl-1H-indole-3-carbaldehyde

Product 1

HCID 183851025-fluoro-1-methyl-1H-indole-3-carboxylic acid

Sources & evidence

ORD record
ord-eade2560774045849c7640d2f895aac7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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