4-(Methanesulfonyl)piperidine → 2-Chloro-6-(4-methanesulfonyl-piperidin-1-ylmethyl)-4-morpholin-4-yl-thieno[2,3-d]pyrimidine
Reaction equation
[CH3:19][S:20](=[O:21])(=[O:22])[CH:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1.[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH:11]=[O:12])[cH:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:26]1[CH2:25][CH2:24][CH:23]([S:20]([CH3:19])(=[O:21])=[O:22])[CH2:28][CH2:27]1)[cH:10]2Participants
3
Sources & evidence
- ORD record
- ord-e83f5636272749bc85755e8430176c61
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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