Water → N1,N3-dimethyl-N1-(thiazol-2-yl)propane-1,3-diamine

Reaction equation

[Br:8][c:9]1[s:10][cH:11][cH:12][n:13]1.[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][NH:6][CH3:7].[CH:15]([Cl:16])([Cl:17])[Cl:18].[OH2:14]>>[CH3:1][N:2]([CH2:3][CH2:4][CH2:5][NH:6][CH3:7])[c:9]1[s:10][cH:11][cH:12][n:13]1

Participants

Reactant 4

HCID 962Water

HCID 6212Chloroform

HCID 66978N,N'-Dimethyl-1,3-propanediamine

HCID 764302-Bromothiazole

Product 1

HCID 69151207N1,N3-dimethyl-N1-(thiazol-2-yl)propane-1,3-diamine

Sources & evidence

ORD record: ord-dbc997b2a0894e1594a3711e88a55d7e
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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