Methanol → 1-(4-Aminobenzoyl)-4-[(4-fluorophenyl)hydroxymethyl]piperidine
Reaction equation
[BH4-:1].[CH3:27][OH:28].[NH2:3][c:4]1[cH:5][cH:6][c:7]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH:13]([C:16]([c:17]3[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]3)=[O:24])[CH2:14][CH2:15]2)[cH:25][cH:26]1.[Na+:2]>>[NH2:3][c:4]1[cH:5][cH:6][c:7]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH:13]([CH:16]([c:17]3[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]3)[OH:24])[CH2:14][CH2:15]2)[cH:25][cH:26]1Participants
5
Sources & evidence
- ORD record
- ord-7924dc2e357844b6ad8e4b9d0a380625
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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