Ammonia → 2-Amino-3,6-dichloro-5-trifluoromethylpyridine

Reaction equation

[CH3:16][OH:17].[Cl:2][c:3]1[c:4]([O:14][CH3:15])[n:5][c:6]([Cl:13])[c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1.[NH3:1]>>[NH2:1][c:4]1[c:3]([Cl:2])[cH:8][c:7]([C:9]([F:10])([F:11])[F:12])[c:6]([Cl:13])[n:5]1

Participants

Reactant 3

HCID 222Ammonia

HCID 887Methanol

HCID 186895102,5-Dichloro-6-methoxy-3-trifluoromethylpyridine

Product 1

HCID 130641542-Amino-3,6-dichloro-5-trifluoromethylpyridine

Sources & evidence

ORD record: ord-95d81d64cbcb471c8002bd59ea96c5aa
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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