2-Fluoro-4-(trifluoromethyl)benzoyl chloride → 5-(N-[2-fluoro-4-trifluoromethylbenzoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

HRID 959460

Reaction equation

HRID 959460 reaction equation
[F:18][c:19]1[c:20]([C:21](=[O:22])[Cl:23])[cH:24][cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[cH:27]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[c:8]([CH:11]1[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH2:16]1)[cH:9][nH:10]2>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[c:8]([CH:11]1[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH2:16]1)[cH:9][nH:10]2)[C:21]([c:20]1[c:19]([F:18])[cH:27][c:26]([C:28]([F:29])([F:30])[F:31])[cH:25][cH:24]1)=[O:22]

Participants

3

Reactant 2

HCID 1455802-Fluoro-4-(trifluoromethyl)benzoyl chlorideHCID 102202303-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine

Product 1

HCID 196015875-(N-[2-fluoro-4-trifluoromethylbenzoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

Sources & evidence

ORD record
ord-78a89fb5187c4b2db4632ab5c2c07631
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Linked notes

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