Ethanol → (6-Chloro-2-methoxy-pyrimidin-4-yl)-[2-(3,4-difluoro-phenyl)-ethyl]-amine
Reaction equation
[CH3:23][CH2:24][OH:25].[Cl:1][c:2]1[n:3][c:4]([O:9][CH3:10])[n:5][c:6]([Cl:8])[cH:7]1.[F:11][c:12]1[cH:13][c:14]([CH2:19][CH2:20][NH2:21])[cH:15][cH:16][c:17]1[F:18].[OH2:22]>>[c:2]1([NH:21][CH2:20][CH2:19][c:14]2[cH:13][c:12]([F:11])[c:17]([F:18])[cH:16][cH:15]2)[n:3][c:4]([O:9][CH3:10])[n:5][c:6]([Cl:8])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-ac531d140e43474980e5318f7268afce
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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