Methanol → 3-Amino-5-bromo-4-hydroxybenzonitrile

HRID 960810

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][c:8]([N+:11]([O-:12])=[O:13])[c:9]1[OH:10].[CH3:16][OH:17].[Cl:18][Fe:19]([Cl:20])[Cl:21].[NH2:14][NH2:15]>>[Br:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][c:8]([NH2:11])[c:9]1[OH:10]

Participants

Reactant 4

HCID 887Methanol

HCID 9321Hydrazine

HCID 24380Iron chloride (FeCl3)

HCID 3014048Benzonitrile, 3-bromo-4-hydroxy-5-nitro-

Product 1

HCID 671407903-Amino-5-bromo-4-hydroxybenzonitrile

Sources & evidence

ORD record: ord-3d5ea251ba154acb8f3198c4c908f27c
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Linked notes

Loading…