4-methyl-8-(piperidin-4-ylmethyl)4H-benzo[1,4]oxazin-3-one → 8-{1-[2-(7-Chloro-2-methylquinolin-5-yloxy)ethyl]piperidin-4-ylmethyl}-4-methyl-4H-benzo[1,4]oxazin-3-one
Reaction equation
[Br:20][CH2:21][CH2:22][O:23][c:24]1[c:25]2[cH:26][cH:27][c:28]([CH3:35])[n:29][c:30]2[cH:31][c:32]([Cl:34])[cH:33]1.[CH3:1][N:2]1[C:3](=[O:19])[CH2:4][O:5][c:6]2[c:7]1[cH:8][cH:9][cH:10][c:11]2[CH2:12][CH:13]1[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]1>>[CH3:1][N:2]1[C:3](=[O:19])[CH2:4][O:5][c:6]2[c:7]1[cH:8][cH:9][cH:10][c:11]2[CH2:12][CH:13]1[CH2:14][CH2:15][N:16]([CH2:21][CH2:22][O:23][c:24]2[c:25]3[cH:26][cH:27][c:28]([CH3:35])[n:29][c:30]3[cH:31][c:32]([Cl:34])[cH:33]2)[CH2:17][CH2:18]1Participants
3
Sources & evidence
- ORD record
- ord-b4da7c60db2144c68b3242edfc6b2578
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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