→ methyl 6-methyl-4-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

HRID 962323

Reaction equation

HRID 962323 reaction equation
CCO.COC(=O)CC(C)=O.Cc1ccc(C=O)cc1.NC(N)=S.O.O.O.O.O.O.O.[Cl-].[Cl-].[Cl-].[La+3]>>COC(=O)C1=C(C)NC(=S)NC1c1ccc(C)cc1

Participants

6

Reactant 0

No Reactant data yet.

Product 1

HCID 2866957methyl 6-methyl-4-(4-methylphenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylateYield 58%

Reagents, catalysts & solvents 5

HCID 702EthanolOther2×HCID 77254-MethylbenzaldehydeOtherHCID 7757Methyl acetoacetateOtherHCID 165791Lanthanum chloride heptahydrateOtherHCID 2723790ThioureaOther

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. filtrationKeep solid
  3. washNo procedure recorded
  4. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-3a3381f514a04fae8775afff4498d279
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Linked notes

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