Methyl 3-methoxybenzoate → 2-(3-Methoxyphenyl)-2-propanamine

HRID 962701

Reaction equation

HRID 962701 reaction equation
CO[C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH2:12])([CH3:11])[CH3:10])=[CH:5][CH:4]=1.[CH3:13][O:14]C1C=C(C=CC=1)C(OC)=O>>[CH3:13][O:14][C:8]1[CH:7]=[C:6]([C:9]([NH2:12])([CH3:10])[CH3:11])[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 79332Methyl 3-methoxybenzoateHCID 110082782-(4-Methoxyphenyl)propan-2-amine

Product 1

HCID 139113102-(3-Methoxyphenyl)-2-propanamineYield 31%

Procedure

Following a procedure similar to that described in Preparation 10a, but using methyl 3-methoxybenzoate as a starting material, in a relative amount similar to that used in that Preparation, the title compound was obtained in a yield of 31%.

Workup

  1. customin a relative amount similar to that used in that Preparation

Sources & evidence

ORD record
ord-af5b5a28152f4b0bae00c8228e3180ff
Source dataset
uspto-grants-1998_06
Patent number
US05760025

Linked notes

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