2-Propanethiol → {3-[(Isopropylthio)methyl]-5-[4-(trifluoromethyl)phenyl]thien-2-yl}methanol
Reaction equation
Br[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=2)[S:5][C:4]=1[C:18]([O:20]CC)=O.[CH3:23][CH:24]([SH:26])[CH3:25]>>[CH:24]([S:26][CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:9]=[CH:10][C:11]([C:14]([F:15])([F:17])[F:16])=[CH:12][CH:13]=2)[S:5][C:4]=1[CH2:18][OH:20])([CH3:25])[CH3:23]Participants
3
Procedure
Prepared from intermediate 43 and isopropylthiol
Sources & evidence
- ORD record
- ord-ae8b6db692d04441a65dd7b35c322628
- Source dataset
- uspto-grants-2006_08
- Patent number
- US07091237B2
Reaction notes
Loading…