HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-acetylhexanoate → HCID 178441161, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-acetylhexanoate | HCID 95466 | — |
| Reactant | Carbonic acid-guanidine (1:1) | HCID 286947 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178441161 | HCID 178441161 | 47.6% |
Reaction Steps
A mixture of ethyl 2-acetylhexanoate (5.59 g, 30 mmol), guanidine carbonate (6.49 g, 30 mmol) and ethanol (20 ml) was refluxed for 11 hours and then ice-cooled. The precipitated crystals were filtered, washed with ethanol and dried in vacuo to give 2-amino-5-butyl-6-methylpyrimidine-4-ol (2.59 g, 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06951866B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-3efbba5677c24c3e998d3b7c5509d1a6 |
| Source note | uspto-grants-2005_10 |