Chlorosulfonic acid → Ethyl 2-(4-(chlorosulfonyl)-2-ethylphenoxy)acetate

Participants

Reaction Steps

A solution of crude ethyl(2-ethylphenoxy)acetate (intermediate 107) in chloroform (6 ml) was stirred with chlorosulfonic acid (1.33 ml) at ambient temperature for 4 hours. The reaction mixture was quenched by the addition of ice and the organic mixture separated by using a hydrophobic frit. The title compound was isolated by evaporation of this filtrate.

Provenance & Evidence