Hexanamide, 2-hydroxy- → 5-Butyloxazolidine-2,4-dione

HRID 967352

Reaction equation

HRID 967352 reaction equation
OC(CCCC)C(N)=O.[Na].[CH2:11]([CH:15]1[O:19][C:18](=[O:20])[NH:17][C:16]1=[O:21])[CH2:12][CH2:13][CH3:14]>>[CH2:11]([CH:15]1[O:19][C:18](=[O:20])[NH:17][C:16]1=[O:21])[CH2:12][CH2:13][CH3:14]

Participants

3

Reactant 2

HCID 9833961Hexanamide, 2-hydroxy-2×HCID 697451525-Butyl-oxazolidin-2,4-dione sodium salt

Product 1

HCID 99422045-Butyloxazolidine-2,4-dione

Procedure

A part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of the starting material 2-hydroxyhexanoic acid amide was 1.3 mass % in the solution and the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 25.9 mass % in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 93.8% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 88.7%.

Workup

  1. aliquotA part of the reaction solution was sampled

Sources & evidence

ORD record
ord-982b82a241964626b2262cc05b40d0c2
Source dataset
uspto-grants-2005_10
Patent number
US06953859B2

Linked notes

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