Deoxyadenosine → (2s,3r,5s)-5-(6-Amino-9h-Purin-9-Yl)-Tetrahydro-2-(Hydroxymethyl)furan-3-Ol

HRID 968507Notes

Reaction equation

HRID 968507 reaction equation
[CH2:1]1[C@H:5]([N:6]2[C:10]3[N:11]=[CH:12][N:13]=[C:14]([NH2:15])[C:9]=3[N:8]=[CH:7]2)[O:4][C@H:3]([CH2:16][OH:17])[C@H:2]1[OH:18]>O>[CH2:1]1[C@@H:5]([N:6]2[C:10]3[N:11]=[CH:12][N:13]=[C:14]([NH2:15])[C:9]=3[N:8]=[CH:7]2)[O:4][C@@H:3]([CH2:16][OH:17])[C@@H:2]1[OH:18]

Participants

3

Reactant 1

HCID 13730Deoxyadenosine

Product 1

HCID 489519(2s,3r,5s)-5-(6-Amino-9h-Purin-9-Yl)-Tetrahydro-2-(Hydroxymethyl)furan-3-Ol

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

αD+26° (c 0.5 water) (commercial 2′-deoxy-D-adenosine-25° (c 0.5 water)).

Sources & evidence

ORD record
ord-d80e56ee94354fd0acf6f6bb2bb3658a
Source dataset
uspto-grants-2007_12
Patent number
US07304043B2

Reaction notes

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