Methyl 2-bromomethyl-5-[4-(trifluoromethyl)phenyl]-3-furoate → {2-[(Quinolin-2-ylthio)methyl]-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

HRID 9686

Reaction equation

HRID 9686 reaction equation
Br[CH2:2][C:3]1[O:4][C:5]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=2)=[CH:6][C:7]=1[C:8]([O:10]C)=O.[N:22]1[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH:25]=[CH:24][C:23]=1[SH:32]>>[N:22]1[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH:25]=[CH:24][C:23]=1[S:32][CH2:2][C:3]1[O:4][C:5]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=2)=[CH:6][C:7]=1[CH2:8][OH:10]

Participants

3

Reactant 2

HCID 21986318Methyl 2-bromomethyl-5-[4-(trifluoromethyl)phenyl]-3-furoate2×HCID 178418736HCID 178418736, compound

Product 1

HCID 21986548{2-[(Quinolin-2-ylthio)methyl]-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

Procedure

The title compound was prepared using methyl 2-(bromomethyl)-5-[4-(trifluoromethyl)phenyl]-3-furoate (intermediate 44) and 2-quinolinethiol.

Sources & evidence

ORD record
ord-2d49faf75f5843e2981edc18336faa55
Source dataset
uspto-grants-2006_08
Patent number
US07091237B2

Linked notes

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