5-Ethynylpyridin-2-amine → 5-[5-(4-Chloro-phenyl)-7-propyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridin-2-ylamine

Reaction equation

[C:21](#[CH:22])[c:23]1[cH:24][cH:25][c:26]([NH2:29])[n:27][cH:28]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH2:14][CH2:15][CH3:16])[cH:13]2)[n:17][cH:18][c:19]3[I:20])[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([CH2:14][CH2:15][CH3:16])[cH:13]2)[n:17][cH:18][c:19]3[C:22]#[C:21][c:23]2[cH:24][cH:25][c:26]([NH2:29])[n:27][cH:28]2)[cH:6][cH:7]1

Participants

Reactant 2

HCID 219548275-Ethynylpyridin-2-amine

HCID 670009495-(4-Chloro-phenyl)-3-iodo-7-propyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 670008915-[5-(4-Chloro-phenyl)-7-propyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-pyridin-2-ylamine

Sources & evidence

ORD record: ord-85c71e09381d49eebd70ec85d6eff7a2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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