(-)-Asparagine → Sodium Aspartate Succinimide

HRID 9707

Reaction equation

HRID 9707 reaction equation
[NH2:1][C@H:2]([C:7]([O-:9])=[O:8])[CH2:3][C:4]([O-:6])=[O:5].[Na+:10].[Na+].N[C@H:13]([C:18]([OH:20])=O)[CH2:14][C:15](=[O:17])[NH2:16].C1(=O)NC(=O)CC1>O>[NH2:1][C@H:2]([C:7]([O-:9])=[O:8])[CH2:3][C:4]([O-:6])=[O:5].[Na+:10].[Na+:10].[C:18]1(=[O:20])[NH:16][C:15](=[O:17])[CH2:14][CH2:13]1

Participants

5

Reactant 3

HCID 6267(-)-AsparagineHCID 11439SuccinimideHCID 21806L-Aspartic acid, sodium salt (1:2)

Product 1

HCID 86597320Sodium Aspartate Succinimide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The reactions and procedures of this Example were repeated, except that the monomer ratios of ammonium aspartate and sodium aspartate were adjusted (in part A) to produce a 1:2 copolymer of sodium aspartate and succinimide. A solution of this copolymer was titrated to pH 4.0 and ring-closed as above. The resulting terpolymer of sodium aspartate, asparagine, and succinimide had a residue ratio of 0.53:10.97 (asp:asn:suc). This terpolymer also was water-soluble.

Workup

  1. customring-closed as above

Sources & evidence

ORD record
ord-2f3cd46004c1483d8835a009998eb43c
Source dataset
uspto-grants-2006_08
Patent number
US07091305B2

Linked notes

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