HCID 22601494, compound → N-benzyl-3-formyl-benzenesulfonamide
Reaction equation
[CH2:1]([NH:8][S:9]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH2:18][OH:19])[CH:13]=1)(=[O:11])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(Cl)Cl.O=[Mn]=O>[CH2:1]([NH:8][S:9]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH:18]=[O:19])[CH:13]=1)(=[O:11])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
Reaction N-Benzyl-3-hydroxymethyl-benzenesulfonamide (crude from previous step, 1.36 mmol), MnO2 (1.40 g, 13.60 mmol) in CH2Cl2 (10 mL) at 40° C. under N2 overnight gave the title compound (317 mg, 85%) as a white solid.
Sources & evidence
- ORD record
- ord-c0ad55d98a454128960a54c5aef7a6b9
- Source dataset
- uspto-grants-2007_12
- Patent number
- US07312234B2
Reaction notes
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