4-(4-Phenoxyphenyl)piperidine → 2-Benzyl-1-[4-(4-(4-phenoxyphenyl)piperidin-1-yl)butyrylamino]benzene

HRID 971

Reaction equation

HRID 971 reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:20])[CH2:16][CH2:17][CH2:18]Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:21]([C:28]1[CH:33]=[CH:32][C:31]([CH:34]2[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]2)=[CH:30][CH:29]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:20])[CH2:16][CH2:17][CH2:18][N:37]1[CH2:38][CH2:39][CH:34]([C:31]2[CH:32]=[CH:33][C:28]([O:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:29][CH:30]=2)[CH2:35][CH2:36]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 110759844-(4-Phenoxyphenyl)piperidineHCID 196942302-Benzyl-1-(4-bromobutyrylamino)benzene

Product 1

HCID 196942372-Benzyl-1-[4-(4-(4-phenoxyphenyl)piperidin-1-yl)butyrylamino]benzene

Procedure

The compound (11) synthesized in Reference Example 11 and the compound (4) synthesized in Reference Example 4 were used to produce the above compound in the same way as Example 1.

Workup

  1. customto produce the above compound in the same way as Example 1

Sources & evidence

ORD record
ord-e1e8c0f8715845c883b3981c2fc0fb5d
Source dataset
uspto-grants-1998_03
Patent number
US05723475

Linked notes

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