Iodobenzene → 5-Ethyl-1-phenyl-1H-pyridin-2-one

Reaction equation

I[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:8]([C:10]1[CH:11]=[CH:12][C:13](=[O:16])[NH:14][CH:15]=1)[CH3:9]>>[CH2:8]([C:10]1[CH:11]=[CH:12][C:13](=[O:16])[N:14]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[CH:15]=1)[CH3:9]

Participants

Reactant 2

HCID 11575Iodobenzene

HCID 193658715-Ethyl-2-pyridinol

Product 1

HCID 101303775-Ethyl-1-phenyl-1H-pyridin-2-oneYield 84%

Procedure

Iodobenzene when caused to react with 5-ethyl-2-(1H)-pyridone following the general procedure outlined in Example 1, an 84% yield of 5-ethyl-1-phenyl-2-(1H)-pyridone is obtained.

Sources & evidence

ORD record: ord-f4c2768575554b058be52c7be33ecc47
Source dataset: uspto-grants-1977_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04052509

Reaction notes

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