1,2-Thiazol-3-amine → HCID 20557906, compound

Reaction equation

NC1C=CSN=1.C([NH:15][C:16]([NH:18][CH2:19][CH2:20][CH2:21][NH:22][C:23]1[CH:27]=[CH:26][S:25][N:24]=1)=[S:17])(=O)C1C=CC=CC=1>>[S:25]1[CH:26]=[CH:27][C:23]([NH:22][CH2:21][CH2:20][CH2:19][NH:18][C:16]([NH2:15])=[S:17])=[N:24]1

Participants

Reactant 2

HCID 128367601,2-Thiazol-3-amine

HCID 20557626N-benzoyl-N'-[3-(3-isothiazolylamino)propyl)thiourea

Product 1

HCID 20557906HCID 20557906, compound

Procedure

By the same procedure, using 3-aminoisothiazole, N-benzoyl-N'-[3-(3-isothiazolylamino)propyl]thiourea is prepared and the benzoyl group is removed to give N-[3-(3-isothiazolylamino)propyl]thiourea.

Workup

customis prepared
customthe benzoyl group is removed

Sources & evidence

ORD record: ord-7f31c381909f407086c4397a36d07986
Source dataset: uspto-grants-1977_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04053473

Reaction notes

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