HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylhomopiperazine → 3-Cyano-2-pyridone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylhomopiperazine | HCID 228349 | — |
| Reactant | 6-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile | HCID 2765203 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 3-Cyano-2-pyridone | HCID 577543 | — |
Reaction Steps
From 12.9 g. of 6-(p-fluorophenyl)-1,2-dihydro-2-oxonicotinonitrile and 13.8 g. of N-methylhomopiperazine in 180 ml. of dimethyl sulfoxide, there is obtained 6-[p-hexahydro-4-methyl-1H-1,4-diazepin-1-yl)phenyl]-1,2-dihydro-2-oxonicotinonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04053470 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-c243a54c7755405bbe0f6fee84b3a5ed |
| Source note | uspto-grants-1977_10 |