Ammonia → 5-(4-Methoxyphenyl)-7-(1-methylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Reaction equation

[CH2:23]1[O:24][CH2:25][CH2:26][O:27][CH2:28]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:19]([CH3:20])[CH3:21])[cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([O:17][CH3:18])[cH:15][cH:16]1.[NH3:22]>>[c:2]1([NH2:22])[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:19]([CH3:20])[CH3:21])[cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([O:17][CH3:18])[cH:15][cH:16]1

Participants

Reactant 3

HCID 222Ammonia

HCID 312751,4-Dioxane

HCID 195974834-Chloro-7-isopropyl-5-(4-methoxyphenyl)pyrrolo[2,3-d]pyrimidine

Product 1

HCID 195974095-(4-Methoxyphenyl)-7-(1-methylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Sources & evidence

ORD record: ord-5c477ec621944db5ac83493ba63f3067
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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