Water → 1-Bromo-3,7-dimethyloctane
Reaction equation
[CH3:1][CH:2]([CH2:6][CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10])[CH2:3][CH2:4]O.P(Br)(Br)[Br:13].O>CCCCCC>[CH3:1][CH:2]([CH2:6][CH2:7][CH2:8][CH:9]([CH3:11])[CH3:10])[CH2:3][CH2:4][Br:13]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 60 °C
Procedure
To neat 3,7-dimethyloctanol (5 ml) was added phosphorus tribromide (1.01 ml). The mixture was stirred for 4 hours at 60° C. The reaction mixture was added to a mixture of water and n-hexane. The organic layer was separated and dried over magnesium sulfate. The magnesium sulfate was filtered off, and the filtrate was evaporated under reduced pressure to give 3,7-dimethyloctyl bromide (4.40 g).
Workup
- customThe organic layer was separated
- dry with materialdried over magnesium sulfate
- filtrationThe magnesium sulfate was filtered off
- customthe filtrate was evaporated under reduced pressure
Sources & evidence
- ORD record
- ord-3494bf0f116242de84cf8586d6e3cba3
- Source dataset
- uspto-grants-1997_03
- Patent number
- USH0001638
Reaction notes
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