2-Acetylfuran → 1-(2-Furyl)-1-(1,3,5-trimethyl-4-pyrazolyl)ethanol

HRID 975072

Reaction equation

Br[C:2]1[C:3]([CH3:9])=[N:4][N:5]([CH3:8])[C:6]=1[CH3:7].[C:10]([C:13]1[O:14][CH:15]=[CH:16][CH:17]=1)(=[O:12])[CH3:11]>>[O:14]1[CH:15]=[CH:16][CH:17]=[C:13]1[C:10]([C:2]1[C:3]([CH3:9])=[N:4][N:5]([CH3:8])[C:6]=1[CH3:7])([OH:12])[CH3:11]

Participants

Reactant 2

HCID 145052-Acetylfuran

HCID 5191814-Bromo-1,3,5-trimethylpyrazole

Product 1

HCID 189363301-(2-Furyl)-1-(1,3,5-trimethyl-4-pyrazolyl)ethanol

Procedure

4-Bromo-1,3,5-trimethylpyrazole was converted into the corresponding 4-lithio compound which was then reacted in situ with 2-acetylfuran.

Sources & evidence

ORD record: ord-da22b7f854a045398ba419874cf31424
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05607956

Linked notes

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