5-Acetyl-2,4-dimethyloxazole → 1-(4-Bromo-3-furyl)-1-(2,4-dimethyl-5-oxazolyl)ethanol

HRID 975075

Reaction equation

HRID 975075 reaction equation
[C:1]([C:4]1[O:8][C:7]([CH3:9])=[N:6][C:5]=1[CH3:10])(=[O:3])[CH3:2].[Br:11][C:12]1[C:13]([Li])=[CH:14][O:15][CH:16]=1>>[Br:11][C:12]1[C:13]([C:1]([C:4]2[O:8][C:7]([CH3:9])=[N:6][C:5]=2[CH3:10])([OH:3])[CH3:2])=[CH:14][O:15][CH:16]=1

Participants

3

Reactant 2

HCID 3184185-Acetyl-2,4-dimethyloxazoleHCID 178418340HCID 178418340, compound

Product 1

HCID 199708911-(4-Bromo-3-furyl)-1-(2,4-dimethyl-5-oxazolyl)ethanol

Procedure

Following the general method of Example 1a but using 5-acetyl-2,4-dimethyloxazole and 4-bromo-3-lithiofuran (Liebigs Ann. Chem., 1986, 625-637), the title compound was prepared.

Sources & evidence

ORD record
ord-6281253b300842e39b4b08f721ddb383
Source dataset
uspto-grants-1997_03
Patent number
US05607956

Linked notes

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