Benzyl Alcohol → HCID 19972025, compound

Reaction equation

[C:1]([O:5][C:6]([NH:8][CH2:9][P:10]([CH2:13][NH:14][C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])(=[O:12])[OH:11])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:22](O)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[C:1]([O:5][C:6]([NH:8][CH2:9][P:10]([CH2:13][NH:14][C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])(=[O:11])[O:12][CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 244Benzyl Alcohol

HCID 11120883HCID 11120883, compound

Product 1

HCID 19972025HCID 19972025, compoundYield 55%

Procedure

In analogy to Example 4, the benzyl phosphinate 5 was prepared from the phosphinic acid 1 and benzyl alcohol in a yield of 55%.

Sources & evidence

ORD record: ord-61ff1298860e48d5867f06d2ee3b7a68
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05608098

Reaction notes

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