2-Bromobutane → 1-Benzyloxy-1-(1-methylpropyl)-3-phenylurea

HRID 976638

Reaction equation

Br[CH:2]([CH2:4][CH3:5])[CH3:3].[CH2:6]([O:13][NH:14][C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:16])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[CH2:6]([O:13][N:14]([CH:2]([CH3:3])[CH2:4][CH3:5])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:16])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

Participants

Reactant 2

HCID 65542-Bromobutane

HCID 2542991-(Benzyloxy)-3-phenylurea

Product 1

HCID 199674261-Benzyloxy-1-(1-methylpropyl)-3-phenylureaYield 36.7%

Procedure

Using the general method of Compound 42 Part B, 2-bromobutane (2.37 mL, 21.7 mmole) was reacted with 1-benzyloxy-3-phenylurea (4.87 g, 20.1 mmole) to provide 2.2 g of 1-benzyloxy-1-(1-methylpropyl)-3-phenylurea.

Sources & evidence

ORD record: ord-4ce32e21a82d4046a56b851e02beded3
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05612377

Linked notes

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