4-(4-Phenoxyphenyl)piperidine → 2-Benzyl-1-[2-(4-(4-phenoxyphenyl)piperidin-1-yl)acetylamino]-6-methylbenzene

HRID 977

Reaction equation

HRID 977 reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[NH:15][C:16](=[O:19])[CH2:17]Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:20]([C:27]1[CH:32]=[CH:31][C:30]([CH:33]2[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]2)=[CH:29][CH:28]=1)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[NH:15][C:16](=[O:19])[CH2:17][N:36]1[CH2:37][CH2:38][CH:33]([C:30]2[CH:31]=[CH:32][C:27]([O:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[CH:28][CH:29]=2)[CH2:34][CH2:35]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 110759844-(4-Phenoxyphenyl)piperidineHCID 196942692-Benzyl-1-(2-bromoacetylamino)-6-methylbenzene

Product 1

HCID 196942572-Benzyl-1-[2-(4-(4-phenoxyphenyl)piperidin-1-yl)acetylamino]-6-methylbenzene

Procedure

The compound (13) synthesized in Reference Example 13 and the compound (4) synthesized in Reference Example 4 were used to produce the above compound in the same way as Example 1.

Workup

  1. customto produce the above compound in the same way as Example 1

Sources & evidence

ORD record
ord-95c8b69826134b41adbfc5c10d2f07c1
Source dataset
uspto-grants-1998_03
Patent number
US05723475

Linked notes

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