4-(4-Phenoxyphenyl)piperidine → 2-Benzyl-1-[4-(4-(4-phenoxyphenyl)piperidin-1-yl)butyrylamino]-6-methylbenzene

HRID 978

Reaction equation

HRID 978 reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[NH:15][C:16](=[O:21])[CH2:17][CH2:18][CH2:19]Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:22]([C:29]1[CH:34]=[CH:33][C:32]([CH:35]2[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]2)=[CH:31][CH:30]=1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:1]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[NH:15][C:16](=[O:21])[CH2:17][CH2:18][CH2:19][N:38]1[CH2:39][CH2:40][CH:35]([C:32]2[CH:33]=[CH:34][C:29]([O:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)=[CH:30][CH:31]=2)[CH2:36][CH2:37]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 110759844-(4-Phenoxyphenyl)piperidineHCID 196942282-Benzyl-1-(4-chlorobutyrylamino)-6-methylbenzene

Product 1

HCID 196942722-Benzyl-1-[4-(4-(4-phenoxyphenyl)piperidin-1-yl)butyrylamino]-6-methylbenzene

Procedure

The compound (14) synthesized in Reference Example 14 and the compound (4) synthesized in Reference Example 4 were used to produce the above compound in the same way as Example 1.

Workup

  1. customto produce the above compound in the same way as Example 1

Sources & evidence

ORD record
ord-9a1a91e08816448db252b1631a3355d4
Source dataset
uspto-grants-1998_03
Patent number
US05723475

Linked notes

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