HuagongsheHuagongshe Chemistry Print Report · For research reference only
Folic Acid → Tetrahydrofolic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Folic Acid | HCID 135398658 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Water | HCID 962 | — |
| Product | Tetrahydrofolic acid | HCID 135444742 | 74.9% |
Reaction Steps
Then, a suspension of 0.0687 g of platinum oxide (containing the noble metal in an amount of 1.5% by weight based on the folic acid) in 50 ml of distilled water was added to the flask, and hydrogenation was carried out in the same manner as described in Example 1 to obtain 2.973 g (74.9% yield) of tetrahydrofolic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04665176 |
| Source dataset | uspto-grants-1987_05 |
| ORD ID | ord-357e9547bcf64640be111d58f575916c |
| Source note | uspto-grants-1987_05 |