Potassium Hydroxide → (1-Methyl-1-ethylpropylamino)ethoxyethanol
Reaction equation
[CH3:1][C:2]([NH2:7])([CH2:5][CH3:6])[CH2:3][CH3:4].Cl[CH2:9][CH2:10][O:11][CH:12]([OH:14])[CH3:13].[OH-].[K+]>COCCO>[CH3:1][C:2]([NH:7][CH2:9][CH2:10][O:11][CH:12]([OH:14])[CH3:13])([CH2:5][CH3:6])[CH2:3][CH3:4]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 124.7 g of 1-methyl-1-ethylpropylamine and 76.9 g of 2-chloroethoxyethanol in 300 ml of ethylene glycol monomethylether was refluxed overnight. The reaction mixture was treated with a stoichiometric excess of KOH and refluxed for one hour, filtered, and distilled. The product had a b.p. of 153° C. (2 mm). Analysis calculated for C10H23NO2 :% N, 7.4, found %N, 7.15.
Workup
- temperaturerefluxed for one hour
- filtrationfiltered
- distillationdistilled
Sources & evidence
- ORD record
- ord-e8016256d9004eda802daf757106c1d7
- Source dataset
- uspto-grants-1987_05
- Patent number
- US04665234
Reaction notes
Loading…