Quinone → HCID 13853736, compound
Reaction equation
[C:1]1(=[O:8])[CH:6]=[CH:5][C:4](=O)[CH:3]=[CH:2]1.[NH2:9][C:10]1[C:15]([O:16][CH3:17])=[CH:14][CH:13]=[CH:12][C:11]=1[SH:18]>CO>[CH3:17][O:16][C:15]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:10]=1[N:9]=[C:4]1[C:3](=[CH:2][C:1](=[O:8])[CH:6]=[CH:5]1)[S:18]2Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a suspension of p-benzoquinone (3.0 g) in 15 ml methanol was added 2-amino-3-methoxythiophenol (2.2 g) dissolved in 10 ml methanol. The mixture was stirred at room temperature for 45 minutes and concentrated in vacuo. The residue was triturated with ether and filtered. The resulting dark solid was chromatographed on silica gel and eluted with EtOAc, to afford the desired compound, m.p. 206°-207°.
Workup
- concentrationconcentrated in vacuo
- customThe residue was triturated with ether
- filtrationfiltered
- customThe resulting dark solid was chromatographed on silica gel
- washeluted with EtOAc
Sources & evidence
- ORD record
- ord-91014a185122430ba7a71587985786f0
- Source dataset
- uspto-grants-1987_05
- Patent number
- US04667032
Reaction notes
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