Sodium Acetate → HCID 13730721, compound
Reaction equation
[C:1]([C:3]([NH:8][C:9](=[O:15])/[CH:10]=[CH:11]\[C:12]([OH:14])=O)([CH3:7])[CH:4]([CH3:6])[CH3:5])#[N:2].C([O-])(=O)C.[Na+]>C(OC(=O)C)(=O)C>[CH:4]([C:3]([CH3:7])([N:8]1[C:9](=[O:15])[CH:10]=[CH:11][C:12]1=[O:14])[C:1]#[N:2])([CH3:6])[CH3:5]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of N-(1-cyano-1,2-dimethylpropyl)maleamic acid (595 g, 2.83 mol) in acetic anhydride (3.96 liters) containing sodium acetate (13.72 g, 0.167 mol) is heated under reflux for one hour, cooled and the solvent removed in vacuo. The product is distilled* at 120°-130° C./0.1 mm to give 337 g (63%) of product.
Workup
- temperatureis heated
- temperatureunder reflux for one hour
- temperaturecooled
- customthe solvent removed in vacuo
- customis distilled* at 120°-130° C.
Sources & evidence
- ORD record
- ord-cbe48fb439c64ab58445ae9d65d16598
- Source dataset
- uspto-grants-1987_01
- Patent number
- US04638068
Reaction notes
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