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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 981Generated: October 25, 2026

1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → N-(2,6-dimethylphenyl)-1-[4-(4-fluorophenyl)methylphenyl]-4-piperazinacetamide

https://huagongshe.com/reaction/981

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 1519998—
Reactant2-bromo-N-(2,6-dimethylphenyl)acetamideHCID 2763487—
ProductN-(2,6-dimethylphenyl)-1-[4-(4-fluorophenyl)methylphenyl]-4-piperazinacetamideHCID 19694242—

Reaction Steps

The compound (18) synthesized in Reference Example 18 and the compound (5) synthesized in Reference Example 5 were used to produce the above compound in the same way as Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723475
Source datasetuspto-grants-1998_03
ORD IDord-63ce7425d0de4ff99768647be804a6c5
Source noteuspto-grants-1998_03