5-Amino-2-chloropyridine → N-[6-Chloropyridin-3-yl]-6-trifluoromethyl-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Reaction equation
[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:7]([n:8]1)[n:9]([CH2:15][c:16]1[cH:17][c:18]([F:22])[cH:19][cH:20][cH:21]1)[c:10]([C:12](=[O:13])[OH:14])[cH:11]2)([F:23])[F:24].[NH2:25][c:26]1[cH:27][n:28][c:29]([Cl:32])[cH:30][cH:31]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]2[c:7]([n:8]1)[n:9]([CH2:15][c:16]1[cH:17][c:18]([F:22])[cH:19][cH:20][cH:21]1)[c:10]([C:12](=[O:14])[NH:25][c:26]1[cH:27][n:28][c:29]([Cl:32])[cH:30][cH:31]1)[cH:11]2)([F:23])[F:24]Participants
3
Sources & evidence
- ORD record
- ord-e53ca88899ce402cb2892cd1326f5f8f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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