HCID 20070371, compound → 1-Propanol, 2-[(2-aminophenyl)amino]-2-methyl-
Reaction equation
[CH3:1][C:2]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-])=O)([CH3:5])[CH2:3][OH:4]>C(O)C.[Pd]>[CH3:5][C:2]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[NH2:13])([CH3:1])[CH2:3][OH:4]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
2-(1,1-dimethyl-2-hydroxyethyl)aminonitrobenzene (10 g) in ethanol (200 ml) was hydrogenated at 50p.s.i. (345 kPa) over 5% Pd/C (0.5 g) for 2 hours. The catalyst was filtered off and the solvent removed under reduced pressure yielding the title compound as a yellow foam 8.4 g (98%).
Workup
- filtrationThe catalyst was filtered off
- customthe solvent removed under reduced pressure
Sources & evidence
- ORD record
- ord-cdeb9fdeb99742dfa3c8a0d9568cd911
- Source dataset
- uspto-grants-1991_02
- Patent number
- US04992447
Reaction notes
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