Water → HCID 20068349, compound

HRID 981861

Reaction equation

HRID 981861 reaction equation
[NH2:1][C:2]1[C:7]([CH3:8])=[C:6]([NH2:9])[CH:5]=[CH:4][C:3]=1[CH3:10].Cl[C:12]1[C:17]([N+:18]([O-])=O)=[CH:16][CH:15]=[CH:14][N:13]=1.C(=O)([O-])[O-:22].[Ca+2].[OH2:26]>>[N+:1]([C:2]1[C:7]([CH3:8])=[C:6]([NH:9][C:12]2[C:17]([NH2:18])=[CH:16][CH:15]=[CH:14][N:13]=2)[CH:5]=[CH:4][C:3]=1[CH3:10])([O-:22])=[O:26]

Participants

5

Reactant 4

HCID 962WaterHCID 10112Calcium CarbonateHCID 796132-Chloro-3-nitropyridineHCID 46255812,4-Dimethylbenzene-1,3-diamine

Product 1

HCID 20068349HCID 20068349, compound

Conditions

Temperature
20 °C

Procedure

8.4 g of 2,4-diamino-m-xylene, 9.6 g of 2-chloro-3nitropyridine and 3.0 g of calcium carbonate were introduced into 300 ml water and the resulting mixture was heated under reflux for 8 hours to the boiling temperature. The reaction mixture was filtered while hot, the reaction product precipitating from the filtrate on cooling to 20° C. It was isolated and recrystallized from toluene. 6.2 g of the product melting at 173° to 175° C. were obtained.

Workup

  1. temperaturethe resulting mixture was heated
  2. temperatureunder reflux for 8 hours to the boiling temperature
  3. filtrationThe reaction mixture was filtered while hot, the reaction product
  4. customprecipitating from the filtrate
  5. customIt was isolated
  6. customrecrystallized from toluene

Sources & evidence

ORD record
ord-83d842d100b547959c007af42c3def27
Source dataset
uspto-grants-1991_02
Patent number
US04994087

Linked notes

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