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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 982Generated: October 24, 2026

1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → 5-[2-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1,5-benzoxazepine

https://huagongshe.com/en/reaction/982

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 1519998—
Reactant5-(2-Bromoacetyl)-2,3,4,5-tetrahydro-1,5-benzoxazepineHCID 19694255—
Product5-[2-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl)acetyl]-2,3,4,5-tetrahydro-1,5-benzoxazepineHCID 19694252—

Reaction Steps

The compound (15) synthesized in Reference Example and the compound (5) synthesized in Reference Example were used to produce the above compound in the same way as Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723475
Source datasetuspto-grants-1998_03
ORD IDord-29980035cd8743d88cbb26a64e2988b5
Source noteuspto-grants-1998_03