2-Buten-1-amine, 3-methyl- → HCID 178446447, compound

HRID 982293

Reaction equation

HRID 982293 reaction equation
[CH3:1][C:2]([CH3:6])=[CH:3][CH2:4][NH2:5].C[N:8](N=O)[C:9]([NH:11][N+:12]([O-:14])=[O:13])=N>CCO.O>[CH3:1][C:2]([CH3:6])=[CH:3][CH2:4][NH:5][C:9]([NH:11][N+:12]([O-:14])=[O:13])=[NH:8]

Participants

4

Reactant 2

HCID 1669212-Buten-1-amine, 3-methyl-HCID 135436526N-Methyl-N'-nitro-N-nitrosoguanidine

Product 1

HCID 178446447HCID 178446447, compound

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

3-methyl-2-butenylamine (3.0 g) is added dropwise at room temperature to a slurry of 1-methyl-3-nitro-1 -nitrosoguanidine (4.3 g) in 50 ml of EtOH/H2O (1/1). After stirring the mixture at room temperature for 18 hours, the precipitate which forms is removed by filtration. The solid is then slurred with dilute hydrochloric acid, collected by filtration and washed with ethanol/water (30/70). Recrystallization from ethanol gives a white solid with mp 134°-136° C.

Workup

  1. customthe precipitate which forms is removed by filtration
  2. filtrationcollected by filtration
  3. washwashed with ethanol/water (30/70)
  4. customRecrystallization from ethanol
  5. customgives a white solid with mp 134°-136° C.

Sources & evidence

ORD record
ord-fc1345d0539b41a2bec5e144a8d474e9
Source dataset
uspto-grants-1991_02
Patent number
US04995903

Linked notes

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