Thionyl Chloride → HCID 22557298, compound
Reaction equation
[O:1]=[C:2]1[NH:7][N:6]=[C:5]([C:8]2[CH:16]=[CH:15][C:11]([C:12](O)=[O:13])=[CH:10][CH:9]=2)[CH2:4][CH2:3]1.S(Cl)([Cl:19])=O>ClCCl>[O:1]=[C:2]1[NH:7][N:6]=[C:5]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([Cl:19])=[O:13])=[CH:10][CH:9]=2)[CH2:4][CH2:3]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
10 mmol (2.2 g) of 4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)benzoic acid are suspended in 50 ml of dichloromethane, after which 1.5 ml (20 mmol) of thionyl chloride are added and the mixture is stirred for 24 hours while being boiled gently.
Sources & evidence
- ORD record
- ord-289c455c455f441f9a3cb3f6ba415f23
- Source dataset
- uspto-grants-2005_03
- Patent number
- US06867206B1
Reaction notes
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