HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylumbelliferone → 7-Methoxychroman-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylumbelliferone | HCID 10748 | — |
| Reactant | 3-(2-Hydroxy-4-methoxy-5-thiocyanato-phenyl)-propionic acid methyl ester | HCID 20765999 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 7-Methoxychroman-2-one | HCID 12389837 | 96% |
Reaction Steps
Compound 14A was prepared by hydrogenation of 7-methoxy-chromen-2-one catalyzed by 10% Pd/C in 96% yield. MS: 179 (M+1)+. Preparation of 3-(2-Hydroxy-4-methoxy-5-thiocyanato-phenyl)-propionic acid methyl ester (Compound 14B)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867224B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-1c2850498de34c9cb7ab5dcc9d76c390 |
| Source note | uspto-grants-2005_03 |